AstraZeneca (AZN) announced that the European Commission (EC) has approved its Zavicefta (ceftazidime-avibactam) for the treatment of serious Gram-negative bacterial infections requiring hospitalization. The approval includes intravenous use for adult patients suffering from complicated intra-abdominal infections, complicated urinary tract infections (including pyelonephritis), hospital-acquired pneumonia (including ventilator-associated pneumonia) and treatment of aerobic Gram-negative infections in adult patients who have limited treatment options.