Viking Therapeutics (VKTX) shares have edged higher in trading today after the company announced positive preclinical results for product candidate VK0214 in a rare nervous system disorder called X-linked adrenoleukodystrophy (X-ALD), a disease caused by the deterioration of fatty covering of nerves (myelin) which reduces the ability of the nerves to relay information to the brain. It also damages the outer layer of the adrenal glands which leads to the shortage of certain hormones (adrenocortical insufficiency). It occurs in ~1 in 17,000 births. The results were generated in a proof-of-concept mouse model of X-ALD. VK0214 rapidly reduced plasma very long chain fatty acid (VLCFA) levels by more than 25% compared to controls after six weeks of treatment. VLCFAs are elevated in X-ALD sufferers due to metabolic defects.